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OncoBlast-GI Oncology Highlights from ASCO 2025: Practice-Changing Trials You Need to Know

This CME-accredited Oncoblast activity is designed to rapidly disseminate key updates in gastrointestinal (GI) oncology from the 2025 ASCO Annual Meeting. Through clinical scenarios and evidence-based insights, participants will review emerging data with implications for standard care across colorectal, gastric, hepatobiliary, and pancreatic cancers.

Course Accreditations

Course Summary

Events StartsEvents Ends
1/1/202512/31/2025

Faculty

Sarbajit Mukherjee   (MD, MS)

Dr. Sarbajit Mukherjee is a board-certified medical oncologist and hematologist specializing in gastrointestinal (GI) malignancies, with a focus on gastroesophageal cancers and cancer immunotherapy. He completed his clinical fellowship in adult hematology-oncology at the University of Oklahoma, where he also earned a Master’s degree in Clinical and Translational Science. His research training at the Oklahoma Medical Research Foundation provided him with extensive laboratory experience, reinforcing his commitment to integrating translational research with patient care. A committed leader in oncology, Dr. Mukherjee has actively contributed to the American Society of Clinical Oncology (ASCO) through various roles, including as a member of the Trainee Council Working Group, Clinical Practice Guidelines Committee, and Professional Development Committee. He has also served on multiple ASCO guideline panels and is currently a panel member at the National Comprehensive Cancer Network (NCCN). Additionally, he sits on the Board of Directors of the Esophageal Cancer Action Network. Dr. Mukherjee has been recognized with numerous honors, including induction into the Alpha Omega Alpha Medical Honor Society and the Gold Humanism Honor Society. He is also a recipient of an ASCO Merit Award. His research is centered on novel clinical trials utilizing circulating tumor DNA (ctDNA) as a biomarker in GI malignancies and investigating the role of obesity in cancer-related immune dysfunction. He has led several investigator-initiated studies, including a Phase II trial funded by the National Cancer Institute (NCI), and has secured competitive grants from the NCCN and the North American Neuroendocrine Tumor Society (NANETS). His work has been featured at leading scientific meetings and published in high-impact journals such as Nature Medicine. He also serves as a peer reviewer for respected journals including Clinical Cancer Research. Dr. Mukherjee views oncology as a holistic discipline that addresses not only disease but also the emotional and psychological journey of each patient. His vision is to be a compassionate clinician, a dedicated researcher, and a thought leader in the field of gastrointestinal cancers.

Disclosure

top-curriculum

    Target Audience

  • Medical Oncologists
  • Surgical and radiation oncologists
  • GI oncology fellows/residents
  • Oncology NPs and PAs
  • Clinical pharmacists
  • Other healthcare providers involved in cancer care

    Learning Objectives

    Upon successful completion of this educational activity, participants will be able to:

  • Summarize pivotal clinical trials in GI cancers presented at ASCO 2025 and their impact on current treatment standards.
  • Integrate biomarker-directed treatment strategies, including immunotherapy and targeted agents, into management plans for GI cancers.
  • Evaluate comparative effectiveness and toxicity profiles of novel regimens to optimize care for diverse GI cancer subtypes.
  • Apply ASCO 2025 updates to real-world clinical decision-making in multidisciplinary GI oncology practice.