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New Prostate Cancer Data From ASCO 2026: PROTEUS, TALAPRO-3, and Treatment Holidays
Cancer Education · Resources for Cancer Patients

New Prostate Cancer Data From ASCO 2026: PROTEUS, TALAPRO-3, and Treatment Holidays

By Dalia Hammoud, MD

Together, PROTEUS, TALAPRO-3, and A-DREAM speak to a broader shift in the field: treatment intensity is increasingly being matched to individual risk and response, rather than applied uniformly.

Practical Updates in Cervical, Ovarian, and Endometrial Cancer From ASCO 2026
Research · Cancer Education

Practical Updates in Cervical, Ovarian, and Endometrial Cancer From ASCO 2026

By Andrew Emmons Green, MD

Not every practice-relevant finding from the 2026 ASCO Annual Meeting comes from a single blockbuster trial.

Bladder Cancer at ASCO 2026: New Standards, Intravesical Approaches, and Enfortumab Vedotin Data

Bladder Cancer at ASCO 2026: New Standards, Intravesical Approaches, and Enfortumab Vedotin Data

By Rosa M. Nadal Rios, MD, PhD

Bladder cancer management in 2026 has been transformed at multiple stages of disease: in non-muscle invasive disease by the arrival of immune checkpoint inhibitors added to BCG

New Drugs, New Standards: What's Changing in Gastroesophageal Cancer Treatment
Cancer Education · Research

New Drugs, New Standards: What's Changing in Gastroesophageal Cancer Treatment

By Allan Pereira, MD, PhD

Gastroesophageal cancers (encompassing adenocarcinomas and squamous cell carcinomas of the esophagus and stomach, including gastroesophageal junction tumors) have seen more treatment advances in the past two years than in the preceding decade.

Upper GI Cancers at ASCO 2026: A New HER2-Positive Standard, a Negative Dual-IO Trial, Signals From Asia
Research · Cancer Education

Upper GI Cancers at ASCO 2026: A New HER2-Positive Standard, a Negative Dual-IO Trial, Signals From Asia

By Dr. Ronan Hsieh

Upper GI cancers remain among the most lethal malignancies worldwide, and the treatment landscape has been evolving rapidly since the approvals of trastuzumab in HER2-positive disease and checkpoint inhibitors across the HER2-negative population.

HCC and Pancreatic Cancer at ASCO 2026: TACE Combinations in Liver Cancer, Daraxonrasib's New Standard
Research · Cancer Education

HCC and Pancreatic Cancer at ASCO 2026: TACE Combinations in Liver Cancer, Daraxonrasib's New Standard

By Rachael A. Safyan, MD

ASCO 2026 brought two late-breaking presentations that are reshaping the treatment of hepatocellular carcinoma and pancreatic cancer.

Colorectal Cancer at ASCO 2026: Stopping Immunotherapy, BRAF-Targeted Therapy, and Exercise's Role
Cancer Education · Research

Colorectal Cancer at ASCO 2026: Stopping Immunotherapy, BRAF-Targeted Therapy, and Exercise's Role

By Stacey A. Cohen, MD

Before discussing any of the specific advances from ASCO 2026, the single most important principle in colorectal cancer is straightforward: test all patients for microsatellite instability (MSI).

Prostate Cancer at ASCO 2026: Perioperative Intensification, Earlier PARP Inhibitors, and De-escalation
Research · Cancer Education

Prostate Cancer at ASCO 2026: Perioperative Intensification, Earlier PARP Inhibitors, and De-escalation

By Alexandra Sokolova, MD

ASCO 2026 brought multiple practice-influencing trials in prostate cancer spanning localized high-risk disease, metastatic hormone-sensitive disease, and de-escalation for exceptional responders.

Cellular Therapies for Multiple Myeloma Part II: CAR-T Toxicities for the Community Oncologist
Research · Cancer Education

Cellular Therapies for Multiple Myeloma Part II: CAR-T Toxicities for the Community Oncologist

By Aimaz Afrough, MD; Samer Al Hadidi, MD, MS; Sean Taasan, MD; Larry D Anderson Jr, MD, PhD

While ide-cel and cilta-cel are generally considered safe and have remarkable therapeutic impact for relapsed/refractory myeloma, both agents carry a broad and clinically significant toxicity burden that practitioners must recognize and actively surveil.

Cellular Therapies for Multiple Myeloma Part I: A CAR-T Primer for the Community Oncologist
Research · Cancer Education

Cellular Therapies for Multiple Myeloma Part I: A CAR-T Primer for the Community Oncologist

By Aimaz Afrough, MD; Samer Al Hadidi, MD, MS; Sean Taasan, MD; Larry D Anderson Jr, MD, PhD

Ide-cel was the first anti-BCMA CAR-T product approved by the FDA in March 2021, employing a single anti-BCMA single-chain variable fragment.

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