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Research
The volume and pace of cancer research, from preclinical studies to clinical trials and FDA approvals, can make it challenging to stay informed. This section highlights the latest developments and translates complex scientific concepts into clear, accessible insights for both healthcare professionals and the broader public.

Combining Immunotherapy With Local Treatment Advances Liver Cancer Care, While a Provocative New Question Emerges About Diabetes Drugs
By Ursa Brown-Glaberman, MD
For more than two decades, transarterial chemoembolization (TACE) has been the standard of care for unresectable hepatocellular carcinoma (HCC) eligible for embolization, typically producing a median progression-free survival of eight to ten months.

Combining Immunotherapy With Local Treatment Advances Liver Cancer Care, While a Provocative New Question Emerges About Diabetes Drugs
By Ursa Brown-Glaberman, MD
For more than two decades, transarterial chemoembolization (TACE) has been the standard of care for unresectable hepatocellular carcinoma (HCC) eligible for embolization, typically producing a median progression-free survival of eight to ten months.

Combining Immunotherapy With Local Treatment Advances Liver Cancer Care, While a Provocative New Question Emerges About Diabetes Drugs
By Ursa Brown-Glaberman, MD
For more than two decades, transarterial chemoembolization (TACE) has been the standard of care for unresectable hepatocellular carcinoma (HCC) eligible for embolization, typically producing a median progression-free survival of eight to ten months.

Targeting Endocrine Resistance: New Sequencing Strategies in Metastatic Breast Cancer
By Jaspreet Kaur, MD
Hormone receptor-positive, HER2-negative metastatic breast cancer that has progressed on a CDK4/6 inhibitor now has multiple biomarker-guided options

Targeting Endocrine Resistance: New Sequencing Strategies in Metastatic Breast Cancer
By Jaspreet Kaur, MD
Hormone receptor-positive, HER2-negative metastatic breast cancer that has progressed on a CDK4/6 inhibitor now has multiple biomarker-guided options

Targeting Endocrine Resistance: New Sequencing Strategies in Metastatic Breast Cancer
By Jaspreet Kaur, MD
Hormone receptor-positive, HER2-negative metastatic breast cancer that has progressed on a CDK4/6 inhibitor now has multiple biomarker-guided options

Advances in the Management of Lung Cancer in 2025 and 2026
By Siddhartha Devarakonda, MD; Carly Irwin, RN, BScN
Recent approvals in NSCLC and SCLC have advanced targeted therapies, immunotherapies, and antibody-drug conjugates across both diseases.

Advances in the Management of Lung Cancer in 2025 and 2026
By Siddhartha Devarakonda, MD; Carly Irwin, RN, BScN
Recent approvals in NSCLC and SCLC have advanced targeted therapies, immunotherapies, and antibody-drug conjugates across both diseases.

Advances in the Management of Lung Cancer in 2025 and 2026
By Siddhartha Devarakonda, MD; Carly Irwin, RN, BScN
Recent approvals in NSCLC and SCLC have advanced targeted therapies, immunotherapies, and antibody-drug conjugates across both diseases.

Leptomeningeal Disease Is Becoming More Common, and Also More Treatable
By Morana Vojnic, MD, MBA
Leptomeningeal disease (LMD) is becoming more common simply because patients with actionable mutations are living longer

Leptomeningeal Disease Is Becoming More Common, and Also More Treatable
By Morana Vojnic, MD, MBA
Leptomeningeal disease (LMD) is becoming more common simply because patients with actionable mutations are living longer

Leptomeningeal Disease Is Becoming More Common, and Also More Treatable
By Morana Vojnic, MD, MBA
Leptomeningeal disease (LMD) is becoming more common simply because patients with actionable mutations are living longer

Rethinking Glioblastoma Care: Methylation Status, Tumor Treating Fields, and IDH Inhibitors
By Jerome Graber, MD, MPH
Glioblastoma outcomes with temozolomide depend heavily on MGMT methylation status, a distinction worth revisiting given how often it gets lost in practice.

Rethinking Glioblastoma Care: Methylation Status, Tumor Treating Fields, and IDH Inhibitors
By Jerome Graber, MD, MPH
Glioblastoma outcomes with temozolomide depend heavily on MGMT methylation status, a distinction worth revisiting given how often it gets lost in practice.

Rethinking Glioblastoma Care: Methylation Status, Tumor Treating Fields, and IDH Inhibitors
By Jerome Graber, MD, MPH
Glioblastoma outcomes with temozolomide depend heavily on MGMT methylation status, a distinction worth revisiting given how often it gets lost in practice.

Sequencing CAR-T and Bispecific Antibodies in Multiple Myeloma: What the Data Show
By Carolina Schinke, MD
CAR-T cell therapy and bispecific antibodies have transformed relapsed multiple myeloma, but sequencing matters.

Sequencing CAR-T and Bispecific Antibodies in Multiple Myeloma: What the Data Show
By Carolina Schinke, MD
CAR-T cell therapy and bispecific antibodies have transformed relapsed multiple myeloma, but sequencing matters.

Sequencing CAR-T and Bispecific Antibodies in Multiple Myeloma: What the Data Show
By Carolina Schinke, MD
CAR-T cell therapy and bispecific antibodies have transformed relapsed multiple myeloma, but sequencing matters.

The Silent Ecosystem Within Clinical Trials
By Zoë Swainson, MHA
Clinical trial outcomes do not emerge solely by science. They also emerge from an invisible ecosystem of trust, coordination, compassion and operational excellence.

The Silent Ecosystem Within Clinical Trials
By Zoë Swainson, MHA
Clinical trial outcomes do not emerge solely by science. They also emerge from an invisible ecosystem of trust, coordination, compassion and operational excellence.

The Silent Ecosystem Within Clinical Trials
By Zoë Swainson, MHA
Clinical trial outcomes do not emerge solely by science. They also emerge from an invisible ecosystem of trust, coordination, compassion and operational excellence.

HER2-Directed Therapy Is Redefining Frontline Treatment for Gastroesophageal Cancer
By Manik Amin, MD
Treatment selection for metastatic gastroesophageal adenocarcinoma now proceeds through a structured biomarker sequence.

HER2-Directed Therapy Is Redefining Frontline Treatment for Gastroesophageal Cancer
By Manik Amin, MD
Treatment selection for metastatic gastroesophageal adenocarcinoma now proceeds through a structured biomarker sequence.

HER2-Directed Therapy Is Redefining Frontline Treatment for Gastroesophageal Cancer
By Manik Amin, MD
Treatment selection for metastatic gastroesophageal adenocarcinoma now proceeds through a structured biomarker sequence.

Novel Agents and MRD-Guided Therapy Are Reshaping Frontline Lymphoma Care
By Joe Schroers-Martin, MD
Bruton's tyrosine kinase (BTK) inhibitor combinations now anchor frontline mantle cell lymphoma treatment across age and fitness categories, including chemotherapy-free regimens for older patients and TP53-mutated disease.

Novel Agents and MRD-Guided Therapy Are Reshaping Frontline Lymphoma Care
By Joe Schroers-Martin, MD
Bruton's tyrosine kinase (BTK) inhibitor combinations now anchor frontline mantle cell lymphoma treatment across age and fitness categories, including chemotherapy-free regimens for older patients and TP53-mutated disease.

Novel Agents and MRD-Guided Therapy Are Reshaping Frontline Lymphoma Care
By Joe Schroers-Martin, MD
Bruton's tyrosine kinase (BTK) inhibitor combinations now anchor frontline mantle cell lymphoma treatment across age and fitness categories, including chemotherapy-free regimens for older patients and TP53-mutated disease.

Advanced Chondrosarcoma Finally Has Systemic Treatment Options Under Study
By Varun Monga, MBBS
Conventional chondrosarcoma has historically had no approved systemic therapy given its resistance to chemotherapy and radiation.

Advanced Chondrosarcoma Finally Has Systemic Treatment Options Under Study
By Varun Monga, MBBS
Conventional chondrosarcoma has historically had no approved systemic therapy given its resistance to chemotherapy and radiation.

Advanced Chondrosarcoma Finally Has Systemic Treatment Options Under Study
By Varun Monga, MBBS
Conventional chondrosarcoma has historically had no approved systemic therapy given its resistance to chemotherapy and radiation.