Friday, October 23, 2026
The Cancer News

AN AUTHORITATIVE RESOURCE FOR EVERYTHING ABOUT CANCER

Cancer Education

Explore expert insights on the fundamentals of cancer, including how it develops, key risk factors, prevention strategies, and treatment options. This section also highlights cancer awareness months and related observance days and weeks. Commentaries from our network of oncology professionals shed light on critical issues that require greater attention across the cancer care and research continuum.

Surgery or Radiation for Stage III Lung Cancer? The Better Question Is Not Which, But When Do We Decide
Cancer Education · Research

Surgery or Radiation for Stage III Lung Cancer? The Better Question Is Not Which, But When Do We Decide

By Neel Chudgar, MD

The surgery-versus-radiation debate in stage III NSCLC is increasingly the wrong framing; the better approach is starting with the best available systemic therapy

Combining Immunotherapy With Local Treatment Advances Liver Cancer Care, While a Provocative New Question Emerges About Diabetes Drugs
Cancer Education · Research

Combining Immunotherapy With Local Treatment Advances Liver Cancer Care, While a Provocative New Question Emerges About Diabetes Drugs

By Ursa Brown-Glaberman, MD

For more than two decades, transarterial chemoembolization (TACE) has been the standard of care for unresectable hepatocellular carcinoma (HCC) eligible for embolization, typically producing a median progression-free survival of eight to ten months.

Targeting Endocrine Resistance: New Sequencing Strategies in Metastatic Breast Cancer
Cancer Education · Research

Targeting Endocrine Resistance: New Sequencing Strategies in Metastatic Breast Cancer

By Jaspreet Kaur, MD

Hormone receptor-positive, HER2-negative metastatic breast cancer that has progressed on a CDK4/6 inhibitor now has multiple biomarker-guided options

Advances in the Management of Lung Cancer in 2025 and 2026
Cancer Education · Research

Advances in the Management of Lung Cancer in 2025 and 2026

By Siddhartha Devarakonda, MD; Carly Irwin, RN, BScN

Recent approvals in NSCLC and SCLC have advanced targeted therapies, immunotherapies, and antibody-drug conjugates across both diseases.

Leptomeningeal Disease Is Becoming More Common, and Also More Treatable
Cancer Education · Research

Leptomeningeal Disease Is Becoming More Common, and Also More Treatable

By Morana Vojnic, MD, MBA

Leptomeningeal disease (LMD) is becoming more common simply because patients with actionable mutations are living longer

Rethinking Glioblastoma Care: Methylation Status, Tumor Treating Fields, and IDH Inhibitors
Cancer Education · Research

Rethinking Glioblastoma Care: Methylation Status, Tumor Treating Fields, and IDH Inhibitors

By Jerome Graber, MD, MPH

Glioblastoma outcomes with temozolomide depend heavily on MGMT methylation status, a distinction worth revisiting given how often it gets lost in practice.

Sequencing CAR-T and Bispecific Antibodies in Multiple Myeloma: What the Data Show
Cancer Education · Research

Sequencing CAR-T and Bispecific Antibodies in Multiple Myeloma: What the Data Show

By Carolina Schinke, MD

CAR-T cell therapy and bispecific antibodies have transformed relapsed multiple myeloma, but sequencing matters.

HER2-Directed Therapy Is Redefining Frontline Treatment for Gastroesophageal Cancer
Cancer Education · Research

HER2-Directed Therapy Is Redefining Frontline Treatment for Gastroesophageal Cancer

By Manik Amin, MD

Treatment selection for metastatic gastroesophageal adenocarcinoma now proceeds through a structured biomarker sequence.

Using MRD Testing to Decide When Multiple Myeloma Maintenance Can Stop
Cancer Education · Perspectives

Using MRD Testing to Decide When Multiple Myeloma Maintenance Can Stop

By Abdullah Mohammad Khan, MBBS

Indefinite lenalidomide maintenance after transplant has been standard practice in multiple myeloma for years, largely on the strength of older trials that never directly tested whether stopping was safe.

Novel Agents and MRD-Guided Therapy Are Reshaping Frontline Lymphoma Care
Cancer Education · Research

Novel Agents and MRD-Guided Therapy Are Reshaping Frontline Lymphoma Care

By Joe Schroers-Martin, MD

Bruton's tyrosine kinase (BTK) inhibitor combinations now anchor frontline mantle cell lymphoma treatment across age and fitness categories, including chemotherapy-free regimens for older patients and TP53-mutated disease.

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