Saturday, October 24, 2026
The Cancer News

AN AUTHORITATIVE RESOURCE FOR EVERYTHING ABOUT CANCER

Cancer Education

Explore expert insights on the fundamentals of cancer, including how it develops, key risk factors, prevention strategies, and treatment options. This section also highlights cancer awareness months and related observance days and weeks. Commentaries from our network of oncology professionals shed light on critical issues that require greater attention across the cancer care and research continuum.

Precision Over Protocol: What's New in HR-Positive, HER2-Negative Breast Cancer
Research · Cancer Education

Precision Over Protocol: What's New in HR-Positive, HER2-Negative Breast Cancer

By Sasha Stanton, MD, PhD

Hormone receptor-positive, HER2-negative (HR+/HER2-) breast cancer is the most common subtype of breast cancer and its treatment landscape has never been more complex or more promising.

CAR-T Cell Therapy for Relapsed Aggressive Lymphoma: Who to Refer, When, and What's Coming Next
Cancer Education · Research

CAR-T Cell Therapy for Relapsed Aggressive Lymphoma: Who to Refer, When, and What's Coming Next

By Paul Shaughnessy, MD

Before CAR-T cell therapy existed, patients with chemotherapy-refractory diffuse large B-cell lymphoma had a median overall survival of 6.3 months, a complete response rate of 7%, and only 20% alive at two years.

New Drugs, New Standards: What's Changing in Gastroesophageal Cancer Treatment
Cancer Education · Research

New Drugs, New Standards: What's Changing in Gastroesophageal Cancer Treatment

By Allan Pereira, MD, PhD

Gastroesophageal cancers (encompassing adenocarcinomas and squamous cell carcinomas of the esophagus and stomach, including gastroesophageal junction tumors) have seen more treatment advances in the past two years than in the preceding decade.

Upper GI Cancers at ASCO 2026: A New HER2-Positive Standard, a Negative Dual-IO Trial, Signals From Asia
Research · Cancer Education

Upper GI Cancers at ASCO 2026: A New HER2-Positive Standard, a Negative Dual-IO Trial, Signals From Asia

By Dr. Ronan Hsieh

Upper GI cancers remain among the most lethal malignancies worldwide, and the treatment landscape has been evolving rapidly since the approvals of trastuzumab in HER2-positive disease and checkpoint inhibitors across the HER2-negative population.

HCC and Pancreatic Cancer at ASCO 2026: TACE Combinations in Liver Cancer, Daraxonrasib's New Standard
Research · Cancer Education

HCC and Pancreatic Cancer at ASCO 2026: TACE Combinations in Liver Cancer, Daraxonrasib's New Standard

By Rachael A. Safyan, MD

ASCO 2026 brought two late-breaking presentations that are reshaping the treatment of hepatocellular carcinoma and pancreatic cancer.

Colorectal Cancer at ASCO 2026: Stopping Immunotherapy, BRAF-Targeted Therapy, and Exercise's Role
Cancer Education · Research

Colorectal Cancer at ASCO 2026: Stopping Immunotherapy, BRAF-Targeted Therapy, and Exercise's Role

By Stacey A. Cohen, MD

Before discussing any of the specific advances from ASCO 2026, the single most important principle in colorectal cancer is straightforward: test all patients for microsatellite instability (MSI).

Prostate Cancer at ASCO 2026: Perioperative Intensification, Earlier PARP Inhibitors, and De-escalation
Research · Cancer Education

Prostate Cancer at ASCO 2026: Perioperative Intensification, Earlier PARP Inhibitors, and De-escalation

By Alexandra Sokolova, MD

ASCO 2026 brought multiple practice-influencing trials in prostate cancer spanning localized high-risk disease, metastatic hormone-sensitive disease, and de-escalation for exceptional responders.

Cellular Therapies for Multiple Myeloma Part II: CAR-T Toxicities for the Community Oncologist
Research · Cancer Education

Cellular Therapies for Multiple Myeloma Part II: CAR-T Toxicities for the Community Oncologist

By Aimaz Afrough, MD; Samer Al Hadidi, MD, MS; Sean Taasan, MD; Larry D Anderson Jr, MD, PhD

While ide-cel and cilta-cel are generally considered safe and have remarkable therapeutic impact for relapsed/refractory myeloma, both agents carry a broad and clinically significant toxicity burden that practitioners must recognize and actively surveil.

Cellular Therapies for Multiple Myeloma Part I: A CAR-T Primer for the Community Oncologist
Research · Cancer Education

Cellular Therapies for Multiple Myeloma Part I: A CAR-T Primer for the Community Oncologist

By Aimaz Afrough, MD; Samer Al Hadidi, MD, MS; Sean Taasan, MD; Larry D Anderson Jr, MD, PhD

Ide-cel was the first anti-BCMA CAR-T product approved by the FDA in March 2021, employing a single anti-BCMA single-chain variable fragment.

Daraxonrasib: The New Pancreatic Cancer Drug Patients Can Access Now Through Clinical Trial
Research · Cancer Education · Resources for Cancer Patients

Daraxonrasib: The New Pancreatic Cancer Drug Patients Can Access Now Through Clinical Trial

By Krutika Gohil, MD

Results of the RASolute 302 clinical trial show Daraxonrasib nearly doubles survival with fewer side effects compared to chemotherapy for pancreatic cancer patients.

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