Friday, July 24, 2026
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Practical Updates in Cervical, Ovarian, and Endometrial Cancer From ASCO 2026
Research · Cancer Education

Practical Updates in Cervical, Ovarian, and Endometrial Cancer From ASCO 2026

By Andrew Emmons Green, MD

Not every practice-relevant finding from the 2026 ASCO Annual Meeting comes from a single blockbuster trial.

Monitoring for Interstitial Lung Disease With Trastuzumab Deruxtecan: A Practice-Changing Case
Cancer Education · Research

Monitoring for Interstitial Lung Disease With Trastuzumab Deruxtecan: A Practice-Changing Case

By Erica Doubleday, NP

Antibody-drug conjugates (ADCs) combine the precision of targeted therapy with the cell-killing power of chemotherapy, and few have been more transformative in breast cancer than fam-trastuzumab deruxtecan (T-DXd)

Refining the Approach to Advanced Ovarian Cancer: New Data From ASCO 2026
Cancer Education · Perspectives

Refining the Approach to Advanced Ovarian Cancer: New Data From ASCO 2026

By Sindhu Priya Devarashetty, MD

Platinum-resistant ovarian cancer remains one of the more difficult clinical scenarios in gynecologic oncology, with a historical overall survival of roughly one year and limited options beyond weekly paclitaxel with or without bevacizumab.

Precision Over Protocol: What's New in HR-Positive, HER2-Negative Breast Cancer
Research · Cancer Education

Precision Over Protocol: What's New in HR-Positive, HER2-Negative Breast Cancer

By Sasha Stanton, MD, PhD

Hormone receptor-positive, HER2-negative (HR+/HER2-) breast cancer is the most common subtype of breast cancer and its treatment landscape has never been more complex or more promising.

CAR-T Cell Therapy for Relapsed Aggressive Lymphoma: Who to Refer, When, and What's Coming Next
Cancer Education · Research

CAR-T Cell Therapy for Relapsed Aggressive Lymphoma: Who to Refer, When, and What's Coming Next

By Paul Shaughnessy, MD

Before CAR-T cell therapy existed, patients with chemotherapy-refractory diffuse large B-cell lymphoma had a median overall survival of 6.3 months, a complete response rate of 7%, and only 20% alive at two years.

Small Cell Lung Cancer in 2026: Tarlatamab Changes the Arc, and a New Wave of ADCs Is Coming
Perspectives · Research

Small Cell Lung Cancer in 2026: Tarlatamab Changes the Arc, and a New Wave of ADCs Is Coming

By Rafael Santana-Davila, MD

Tarlatamab has changed the arc of small cell lung cancer — the first treatment in years to improve survival in the second-line setting. Dr. Rafael Santana-Davila maps the 2026 landscape and the ADC wave that's coming.

Bladder Cancer at ASCO 2026: A New Standard in Non-Muscle Invasive Disease, Intravesical Approaches in Muscle-Invasive Disease, and Three and a Half Years of Enfortumab Vedotin Data

Bladder Cancer at ASCO 2026: A New Standard in Non-Muscle Invasive Disease, Intravesical Approaches in Muscle-Invasive Disease, and Three and a Half Years of Enfortumab Vedotin Data

By Rosa M. Nadal Rios, MD, PhD

Bladder cancer management in 2026 has been transformed at multiple stages of disease: in non-muscle invasive disease by the arrival of immune checkpoint inhibitors added to BCG

New Drugs, New Standards: What's Changing in Gastroesophageal Cancer Treatment
Cancer Education · Research

New Drugs, New Standards: What's Changing in Gastroesophageal Cancer Treatment

By Allan Pereira, MD, PhD

Gastroesophageal cancers (encompassing adenocarcinomas and squamous cell carcinomas of the esophagus and stomach, including gastroesophageal junction tumors) have seen more treatment advances in the past two years than in the preceding decade.

Upper GI Cancers at ASCO 2026: A New HER2-Positive Standard, a Negative Dual-IO Trial, and Two Signals From Asia
Research · Cancer Education

Upper GI Cancers at ASCO 2026: A New HER2-Positive Standard, a Negative Dual-IO Trial, and Two Signals From Asia

By Dr. Ronan Hsieh

Upper GI cancers remain among the most lethal malignancies worldwide, and the treatment landscape has been evolving rapidly since the approvals of trastuzumab in HER2-positive disease and checkpoint inhibitors across the HER2-negative population.

HCC and Pancreatic Cancer at ASCO 2026: TACE Combinations Move Forward in Liver Cancer, and Daraxonrasib Rewrites the Standard of Care in Pancreatic Cancer
Research · Cancer Education

HCC and Pancreatic Cancer at ASCO 2026: TACE Combinations Move Forward in Liver Cancer, and Daraxonrasib Rewrites the Standard of Care in Pancreatic Cancer

By Rachael A. Safyan, MD

ASCO 2026 brought two late-breaking presentations that are reshaping the treatment of hepatocellular carcinoma and pancreatic cancer.

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