Thursday, October 22, 2026
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HER2-Directed Therapy Is Redefining Frontline Treatment for Gastroesophageal Cancer
Cancer Education · Research

HER2-Directed Therapy Is Redefining Frontline Treatment for Gastroesophageal Cancer

By Manik Amin, MD

Treatment selection for metastatic gastroesophageal adenocarcinoma now proceeds through a structured biomarker sequence.

Using MRD Testing to Decide When Multiple Myeloma Maintenance Can Stop
Cancer Education · Perspectives

Using MRD Testing to Decide When Multiple Myeloma Maintenance Can Stop

By Abdullah Mohammad Khan, MBBS

Indefinite lenalidomide maintenance after transplant has been standard practice in multiple myeloma for years, largely on the strength of older trials that never directly tested whether stopping was safe.

Advanced Chondrosarcoma Finally Has Systemic Treatment Options Under Study
Cancer Education · Research

Advanced Chondrosarcoma Finally Has Systemic Treatment Options Under Study

By Varun Monga, MBBS

Conventional chondrosarcoma has historically had no approved systemic therapy given its resistance to chemotherapy and radiation.

Autologous Transplant in Multiple Myeloma: Still the Standard as Quadruplet Therapy and Cellular Immunotherapy Advance
Cancer Education · Research

Autologous Transplant in Multiple Myeloma: Still the Standard as Quadruplet Therapy and Cellular Immunotherapy Advance

By Jason Chandler, MD

Autologous stem cell transplant has anchored newly diagnosed multiple myeloma treatment for decades, and every major guideline body still recommends it for eligible patients.

Immunotherapy Is Moving Earlier Into Head and Neck Cancer Treatment
Cancer Education · Research · Perspectives

Immunotherapy Is Moving Earlier Into Head and Neck Cancer Treatment

By Hyunseok Kang, MD, MPH

Head and neck cancer treatment has historically advanced roughly once a decade, but two meaningful updates are arriving together this year

Perioperative Intensification in High-Risk Prostate Cancer: PROTEUS, TALAPRO-3, and Treatment De-Escalation
Cancer Education · Research

Perioperative Intensification in High-Risk Prostate Cancer: PROTEUS, TALAPRO-3, and Treatment De-Escalation

By Putao Cen, MD

Perioperative intensification is reshaping treatment for high-risk localized and metastatic castration-sensitive prostate cancer.

Overcoming Language Barriers in Cancer Care
Perspectives · Health Equity · Resources for Cancer Patients

Overcoming Language Barriers in Cancer Care

By Kaila Johnson

Language barriers delay cancer diagnoses and lower screening rates for patients with limited English proficiency. Experts weigh in on interpreter access, cultural competence, and why closing these gaps is critical to equitable cancer care.

MDS, MECOM-Rearranged Leukemia, and BPDCN: New Data Reshaping Treatment Choices
Cancer Education · Perspectives

MDS, MECOM-Rearranged Leukemia, and BPDCN: New Data Reshaping Treatment Choices

By Cecilia Arana Yi, MD

The VERONA trial finds venetoclax adds no survival benefit in higher-risk MDS; new data illuminate outcomes in MECOM-rearranged AML and BPDCN, where transplant remains the strongest predictor of survival.

The New Frontier in Lung Cancer Therapy: Targeted Therapy, and Bispecific Antibodies
Research · Cancer Education

The New Frontier in Lung Cancer Therapy: Targeted Therapy, and Bispecific Antibodies

By Robert Lin, MD

Adjuvant targeted therapy already has a track record in early-stage non-small cell lung cancer (NSCLC) driven by EGFR or ALK alterations, where it has meaningfully reduced recurrence after surgery.

Resistance to KRAS Inhibitors Is Multilayered, and Lineage Plasticity Deserves More Attention
Cancer Education · Research

Resistance to KRAS Inhibitors Is Multilayered, and Lineage Plasticity Deserves More Attention

By Konstantin Dragnev, MD

Resistance to KRAS inhibitors should be understood as three distinct categories, primary/intrinsic, adaptive/non-genetic, and acquired/genetic, each with different mechanisms and different implications for how to sequence or combine therapy.

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