Wednesday, June 3, 2026
The Cancer News

AN AUTHORITATIVE RESOURCE FOR EVERYTHING ABOUT CANCER

Triple Negative Breast Cancer in 2026: ADCs Move to the Front, Immunotherapy Stays Central, and Biomarkers Still Lag Behind
Research · Perspectives

Triple Negative Breast Cancer in 2026: ADCs Move to the Front, Immunotherapy Stays Central, and Biomarkers Still Lag Behind

By Nikitha Vobugari, MD

ADCs are moving to the front line in metastatic TNBC, immunotherapy's role in early-stage disease is being refined, and biomarkers still lag behind. Dr. Nikitha Vobugari breaks down where the field stands in 2026.

CAR-T or Bispecific Antibodies First? A Practical Sequencing Guide for Relapsed Multiple Myeloma in 2026
Perspectives · Research

CAR-T or Bispecific Antibodies First? A Practical Sequencing Guide for Relapsed Multiple Myeloma in 2026

By Sean Maximillian Taasan, MD

CAR-T or bispecific antibodies first? A myeloma specialist breaks down the sequencing evidence, IMWG guidance, and practical factors that should guide treatment decisions in relapsed multiple myeloma in 2026.

The Venetoclax Revolution in AML, and Its Limits in MDS: What the PARADIGM and VERONA Trials Mean for Practice
Research · Perspectives

The Venetoclax Revolution in AML, and Its Limits in MDS: What the PARADIGM and VERONA Trials Mean for Practice

By By Bart L. Scott, MD

The PARADIGM and VERONA trials tell two very different stories about venetoclax in myeloid malignancies—a promising shift in AML treatment and a sobering setback in MDS. A leading expert breaks down both.

Belzutifan in 2026: Three Phase 3 Trials, Two Likely Approvals, and One Negative Surprise
Research · Perspectives

Belzutifan in 2026: Three Phase 3 Trials, Two Likely Approvals, and One Negative Surprise

By Scott Tykodi, MD, PhD

Three Phase 3 trials of belzutifan in clear cell RCC reported in 2026: two positive results poised for FDA approval, and one frontline surprise that leaves the current standard of care intact.

Ten Years of CAR-T, and Ten More to Come: A Measured Look at What the Next Decade Will Bring
Perspectives · Research

Ten Years of CAR-T, and Ten More to Come: A Measured Look at What the Next Decade Will Bring

By Sattva S. Neelapu, MD

A CAR-T cell therapy pioneer reflects on a decade of progress and offers measured predictions for 2036—from frontline use and dual-target CARs to in vivo delivery and beyond oncology.

CAR-T Cell Therapy in Follicular Lymphoma and CLL: Identifying the High-Risk Patients Who Need It Most
Cancer Education · Research

CAR-T Cell Therapy in Follicular Lymphoma and CLL: Identifying the High-Risk Patients Who Need It Most

By Bradley W. Christensen, MD

Expert commentary on CAR-T therapy for follicular lymphoma and CLL, focusing on POD24 patients, FLIPI-2 risk, bispecific antibodies, and emerging treatment strategies.

The Hidden Barrier to Precision Oncology: How Insurance Policies Delay Access to Genomic Testing
Cancer Education · Research

The Hidden Barrier to Precision Oncology: How Insurance Policies Delay Access to Genomic Testing

By Ira Klein, MBA, MD, FACP

Dr. Ira Klein explores how outdated insurance policies, prior authorization burdens, and administrative barriers delay equitable access to precision oncology testing.

AI in Breast Diagnostics: Why What We Do With the Tool Matters More Than the Tool Itself
Research · Cancer Education · Perspectives

AI in Breast Diagnostics: Why What We Do With the Tool Matters More Than the Tool Itself

By Benjamin O. Anderson, MD, FACS

Dr. Benjamin O. Anderson explores the promise and limitations of AI in breast diagnostics, emphasizing that patient navigation, infrastructure, and access to care matter more than technology alone.

The Immunotherapy Landscape in Colorectal Cancer: Where We Stand and Where We're Headed
Cancer Education · Research

The Immunotherapy Landscape in Colorectal Cancer: Where We Stand and Where We're Headed

By Ibrahim Halil Sahin, MD

Expert commentary on the evolving role of immunotherapy in colorectal cancer, including MSI-H breakthroughs, MSS challenges, biomarker-driven treatment, and emerging clinical trial strategies.

CAR-T Cell Therapy in Aggressive Lymphoma: Navigating Standard-of-Care Products, Sequencing Strategies, and the Road to Frontline Use
Cancer Education · Research

CAR-T Cell Therapy in Aggressive Lymphoma: Navigating Standard-of-Care Products, Sequencing Strategies, and the Road to Frontline Use

By Elif Yilmaz, MD

Expert commentary on CAR-T cell therapy in aggressive lymphoma, including DLBCL and mantle cell lymphoma, with insights on product selection, toxicity, sequencing strategies, and frontline applications.

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